Professor Dame Pamela Shaw is Professor of Neurology at the University of Sheffield, UK and Director of the Sheffield Institute for Translational Neuroscience (SITraN), one of the world’s leading centers for ALS/MND research. She is a Clinician Scientist in Neurology and formerly a Wellcome Trust Senior Fellow in Clinical Science. Since 1991 she has led a major multidisciplinary program of research investigating genetic, molecular and neurochemical factors underlying neurodegenerative disorders of the human motor system. She has authored more than 500 publications of original research (Google Scholar H-index 104), reviews and book chapters and has edited several books on ALS/MND. Her research is funded by the Medical Research Council, the Wellcome Trust, NIHR, the MND Association, the European Union and biotechnology & pharmaceutical industry partners. She has generated more than £60M in research income since 1983.
Professor Dame Shaw has led the Clinical Studies Group for ALS/MND within the NIHR Dementia and Neurodegenerative Diseases (DeNDRoN) clinical research network, which links 19 ALS/MND Care and Research Centres and has developed a network of 10 UK centres experienced in ALS clinical trials. Professor Shaw has taken part in more than 15 ALS clinical trials, including roles as UK Chief Investigator and Steering Committee member and also including several academic led studies. She is an active member of the European Network for the Cure of ALS (ENCALS). She is the recipient of the Association of British Neurologists Sir Charles Symonds award (1991; 1996; 2001), the American Academy of Neurology Sheila Essey award in 2001, the UK Royal College of Physicians Jean Hunter award in 2006, the International ALS/MND Forbes Norris award in 2007, the Fellowship of the Academy of Medical Sciences in 2007, the Physiological Society GL Brown Prize in 2019, the Queen’s Anniversary Prize in 2019. In 2014 she was awarded the Dame Commander of the Order of the British Empire (DBE) for services to Neuroscience in the HM the Queen’s New Year’s Honours.